Marruganti, CrystalBaima, GiacomoAimetti, MarioGrandini, SimoneSanz Alonso, MarianoRomandini, Mario2024-10-042024-10-042023-04Marruganti C, Baima G, Aimetti M, Grandini S, Sanz M, Romandini M. Periodontitis and low cognitive performance: A population-based study. J Clin Periodontol. 2023 Apr;50(4):418-429. doi: 10.1111/jcpe.137790303-697910.1111/jcpe.13779https://hdl.handle.net/20.500.14352/1086482023 Otros acuerdos transformativos UCMAim: To study the epidemiological association between periodontitis and low cognitive performance among older adults, within a representative sample of the U.S. Materials and methods: Data from 2086 older adults (≥60 years old), representative of 77.1 million people, were retrieved from the NHANES 2011-2014 database. Periodontitis cases were identified and classified according to the AAP/CDC criteria (mild, moderate, and severe). Cognitive function was assessed through the Consortium to Establish a Registry for Alzheimer's disease (CERAD), the animal fluency test (AFT), the digit symbol substitution test (DSST), and the global cognition score. The lowest non-survey weighted quartile for each cognitive test was defined as low cognitive performance. Simple and multiple regression analyses were performed. Results: Moderate and severe periodontitis were significantly associated with a low DSST performance (OR = 1.66 and OR = 2.97, respectively). Each millimetre increase in mean CAL was associated with a lower AFT (OR = 1.44), DSST (OR = 1.86), and global cognition (OR = 1.50) performance. Conclusions: The findings of the present study suggest the existence of an independent association between periodontitis and low cognitive performance among older adults (≥60 years old).engAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/journal article1600-051Xhttps://doi. org/10.1111/jcpe.1377936644802https://pubmed.ncbi.nlm.nih.gov/36644802/https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpe.13779open access616.314.17-008.1159.922.63159.928Alzheimer's diseaseCognitive declineCognitive impairmentNeurocognitive disordersPeriodontal diseasesOdontología (Odontología)PeriodonciaNeurociencias (Medicina)Tercera edad32 Ciencias Médicas2490 Neurociencias5206.03 Envejecimiento de la Población