Miguel Díez, Javier DeAlbaladejo Vicente, RomanaPalacios-Ceña, DomingoCarabantes Alarcón, DavidZamorano León, José JavierLópez Herranz, MartaLópez De Andrés, Ana Isabel2024-02-142024-02-142020de Miguel-Diez J, Albaladejo-Vicente R, Palacios-Ceña D, Carabantes-Alarcon D, Zamorano-Leon JJ, Lopez-Herranz M, Lopez-de-Andres A. The Impact of COPD in Trends of Urinary Tract Infection Hospitalizations in Spain, 2001-2018: A Population-Based Study Using Administrative Data. J Clin Med. 2020 Dec 9;9(12):3979. doi: 10.3390/jcm9123979. PMID: 33316870; PMCID: PMC7763854.10.3390/jcm9123979https://hdl.handle.net/20.500.14352/101434Background: To examine trends in incidence and outcomes of urinary tract infections (UTIs) among men and women with or without chronic obstructive pulmonary disease (COPD), and to identify the predictors for in-hospital mortality (IHM). (2) Methods: We included patients (aged ≥40 years) who were hospitalized with UTIs between 2001 and 2018. Data were collected from the Spanish National Hospital Discharge Database. (3) Results: We identified 748,458 UTI hospitalizations, 6.53% with COPD. The UTIs incidence increased over time. It was 1.55 times higher among men COPD patients than among non-COPD men (incidence rate ratio (IRR) 1.55; 95% CI 1.53-1.56). The opposite happened in women with COPD compared to non-COPD women (IRR 0.30; 95% CI 0.28-0.32). IHM was higher in men with COPD than non-COPD men (5.58% vs. 4.47%; p < 0.001) and the same happened in women (5.62% vs. 4.92%; p < 0.001). The risk of dying increased with age and comorbidity, but the urinary catheter was a protective factor among men (OR 0.75; 95% CI 0.64-0.89). Multivariable analysis showed a significant reduction in the IHM over time for men and women with COPD. Suffering from COPD only increased the risk of IHM among men (OR 1.07; 95% CI 1.01-1.13). (4) Conclusions: The incidence of UTIs increased over time. Suffering COPD increased the risk of IHM among men, but not among women.engAttribution-NonCommercial-NoDerivatives 4.0 Internationaljournal article2077-0383https://doi.org/10.3390/jcm9123979open access616.6616.1/.9Urinary tract infectionCOPDMenWomenIncidenceIn-hospital mortalitySpainCiencias Biomédicas32 Ciencias Médicas