De La Torre Serrano, MontserratAlarcón García, LorenzoColino Gallardo, Ana MaríaVega González, JesúsBergillos Giménez, María ReyesHernández Martínes, DesiréGarcía Egido, AlejandroIglesias Moreno, María CruzPérez Alonso, PabloPlaza Hernández, José CarlosFernández Aceñero, María Jesús2025-04-012025-04-012024-08-21De La Torre Serrano M, Alarcón García L, Colino Gallardo AM, et al. Striated duct adenoma: The cytological description of a rare entity. Cytopathology. 2025; 36: 56-62. doi:10.1111/cyt.134410956-550710.1111/cyt.13441https://hdl.handle.net/20.500.14352/119086Introduction Striated duct adenoma is a benign salivary gland tumour recently recognized by the World Health Organization. To date, no report has described the cytological features of this entity. Materials and Methods We report the case of a 60-year-old woman with a tumour in the right parotid gland with a diameter greater than 2.4 cm confirmed by imaging tests. Results Two fine-needle aspiration cytologies (FNAC) were performed with inconclusive results, reporting epithelioid and spindle-shaped cellularity, with little stroma, and nuclei with abundant pseudoinclusions. Myoepithelioma and Schwannoma were proposed as differential diagnoses. An immunocytochemical panel was performed, showing positivity for S-100, SOX10, CK7 and vimentin, and negativity for both myoepithelial (p63 and calponin) and thyroid markers. In the absence of a conclusive diagnosis, the patient accepted surgery. The biopsy results confirmed diagnosis of striated duct adenoma, with immunohistochemical features superimposable to cytology. Conclusion Little information is available in the literature, both on biopsy and, more strikingly, on cytology of this neoplasm. The aim of this work is to provide cytological characteristics that allow diagnosis of this entity with FNAC and thus avoid unnecessary surgeries.engjournal article1365-2303https://doi.org/10.1111/cyt.13441https://onlinelibrary.wiley.com/doi/full/10.1111/cyt.13441#:~:text=Striated%20duct%20adenoma%20is%20very,in%20the%204B%20Milan%20category.restricted access616-091.8cytologyFNACmyoepithelialpseudoinclusionssalivary glandstriated duct adenomaCiencias Biomédicas32 Ciencias Médicas