Martín Oviedo, CarlosMaranillo Alcaide, EvaSañudo Tejero, José RamónPérez Lloret, PilarVerdu Navarro, EnriqueMartinez Guirado, TomasAlvarez Montero, OscarGomez Martin-Zarco, Jose ManuelVazquez Osorio, Teresa2024-01-122024-01-122018-04-16Martín-Oviedo C, Maranillo E, Sañudo JR, Pérez-Lloret P, Verdú E, Martínez-Guirado T, Álvarez-Montero O, Gómez Martín-Zarco JM, Vázquez T. The human laryngeal innervation revisited-the role of the neural connections. Anat Rec (Hoboken) 2019;302(4):646-651.1932-848610.1002/ar.23817https://hdl.handle.net/20.500.14352/92859In spite that vascular inconvenients or immunological rejections have been solved in relation with larynx transplant, a successful functional reinnervation has not been achieved. Some studies have suggested that laryngeal nerve connection may contain motor fibers, which could explain unexpected evoked responses in electromyographic studies or the different positions adopted of the vocal folds after similar nerve lesions. Ten patients with unexpected evoked responses after laryngeal nerve stimulation were selected. All the patients underwent a total laryngectomy due to oncological causes. In every case, laryngeal nerve connections were observed. All of them were morphologic and histologic processed for choline-acetyltransferase immunohistochemistry. The presence of motor axons in the nerve connections has been demonstrated, which would explain that the motor innervation to the laryngeal muscles could be dual through these variable connections. This also would justify the difficulty of carrying out laryngeal nerve reinnervation procedures.engAttribution 4.0 Internationaljournal article1932-8494https://anatomypubs.onlinelibrary.wiley.com/doi/epdf/10.1002/ar.23817open access636.09laryngeal innervationelectromyographyChAtmotor fiberslaryngectomyCiencias Biomédicas32 Ciencias Médicas