Skolnick, JeffreyKolinski, AndrzejBrooks, Charles L.Godzik, AdamRey, Antonio2023-06-202023-06-2019930960-982210.1016/0960-9822(93)90348-Rhttps://hdl.handle.net/20.500.14352/60167The ability to predict the native conformation of a globular protein from its amino-acid sequence is an important unsolved problem of molecular biology. We have previously reported a method in which reduced representations of proteins are folded on a lattice by Monte Carlo simulation, using statistically-derived potentials. When applied to sequences designed to fold into four-helix bundles, this method generated predicted conformations closely resembling the real ones.engjournal articlehttp://www.cell.com/current-biology/fulltext/0960-9822(93)90348-Ropen access544Química física (Química)