González Regueiro, IriaMartínez Rodriguez, NataliaBarona Dorado, CristinaSanz Sánchez, IgnacioMontero Solís, EduardoAta-Ali, JavierDuarte, FernandoMartínez González, José María2024-01-102024-01-102021-12-21González Regueiro I, Martínez Rodriguez N, Barona Dorado C, et al. Surgical approach combining implantoplasty and reconstructive therapy with locally delivered antibiotic in the treatment of peri-implantitis: A prospective clinical case series. Clin Implant Dent Relat Res. 2021; 23(6): 864-8731523-089910.1111/cid.13049https://hdl.handle.net/20.500.14352/92210Background: Nonsurgical treatment, resective surgery, reconstructive surgery, or combined approaches have been proposed for the treatment of peri-implantitis, with variable results. Purpose: To evaluate the 1-year clinical and radiographic outcomes following combined resective and reconstructive surgical treatment with topical piperacillin/tazobactam antibiotic in the management of peri-implantitis. Material and methods: Forty-three patients diagnosed with peri-implantitis were included. Surgical treatment consisted of implantoplasty of the supra-crestal component of the defect, the application of a topical antibiotic solution over the implant surface, and subsequent reconstruction of the intra-osseous component of the peri-implant defect. The primary outcome was disease resolution, defined as the absence of bleeding on probing (BoP) and/or suppuration on probing (SoP), a peri-implant pocket probing depth (PPD) ≤5 mm, and no bone loss >0.5 mm 1 year after surgery. Secondary outcomes included changes in BoP, PPD, SoP, and peri-implant marginal bone levels. One implant per patient was included in the analysis. Results: The treatment success rate of the 43 dental implants included in the study was 86% at 1 year after surgery. Mean PPD and BoP decreased from 6.41 ± 2.11 mm and 100% at baseline to 3.19 ± 0.99 mm (p < 0.001) and 14% (p < 0.001) at 1 year, respectively. SoP was significantly reduced from 48.8% at baseline to 0% 1 year after surgery (p < 0.001). Radiographically, a mean defect fill of 2.64 ± 1.59 mm was recorded (p < 0.001). Conclusions: The combination of a resective and reconstructive surgical approach together with locally delivered antibiotic achieved a high disease resolution rate after 1 year of follow-up and constitutes a viable option for the management of peri-implantitis.engAttribution-NonCommercial-NoDerivatives 4.0 Internationaljournal article1708-8208https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.1304934651432wileyonlinelibrary.com/journal/cidopen access616.314-089616.314-089.843Bone loss; Case report; Implantoplasty; Local anti-infective agent; Peri-implantitis; Regenerative surgeryCirugía bucofacialImplantes dentales3213 Cirugía32 Ciencias Médicas3213.13 Ortodoncia-Estomatología