Read, Jenny C AGeorgiou, RenosBrash, ClaireYazdani, PartowWhittaker, RogerTrevelyan, Andrew JSerrano Pedraza, Ignacio2023-06-192023-06-1920151534-736210.1167/15.1.5https://hdl.handle.net/20.500.14352/35115A well-studied paradox of motion perception is that, in order to correctly judge direction in high-contrast stimuli, subjects need to observe motion for longer in large stimuli than in small stimuli. This effect is one of several perceptual effects known generally as "surround suppression." It is usually attributed to center-surround antagonism between neurons in visual cortex, believed to be mediated by GABA-ergic inhibition. Accordingly, several studies have reported that this index of surround suppression is reduced in groups known to have reduced GABA-ergic inhibition, including older people and people with schizophrenia and major depressive disorder. In this study, we examined the effect on this index of moderate amounts of ethanol alcohol. Among its many effects on the nervous system, alcohol potentiates GABA-ergic transmission. We therefore hypothesized that it should further impair the perception of motion in large stimuli, resulting in a stronger surround-suppression index. This prediction was not borne out. Alcohol consumption slightly worsened duration thresholds for both large and small stimuli, but their ratio did not change significantly.spajournal articlehttp://dx.doi.org/ 10.1167/15.1.5open access159.9.07159.93EthanolMotion perceptionVisionPsychophysicsSurround suppressionPsicología experimentalPercepciónÓptica oftálmica6106 Psicología Experimental6106.09 Procesos de Percepción