Fernández Lucas, Alberto Amablede Sola, Rafael G.Amo, CarlosTurrero Nogués, AgustínZuluaga Arias, María del PilarMaestu Unturbe, FernandoCampo, PabloOrtiz, Tomás2023-06-202023-06-202004-07Fernández Lucas, A. A., De Sola, R. G., Amo, C. et al. «Dipole Density of Low-Frequency and Spike Magnetic Activity: A Reliable Procedure in Presurgical Evaluation of Temporal Lobe Epilepsy»: Journal of Clinical Neurophysiology, vol. 21, n.o 4, julio de 2004, pp. 254-66. DOI.org (Crossref), https://doi.org/10.1097/00004691-200407000-00004.0736-025810.1097/00004691-200407000-00004https://hdl.handle.net/20.500.14352/51438Conventional visual analysis and dipole density analysis of magnetoencephalographic data for both spike and low-frequency magnetic activity were compared for presurgical evaluation in temporal lobe epilepsy (TLE) in a sample of 26 drug-resistant operated TLE patients. A series of logistic regression analyses were performed. Dipole density sensitivity was superior to visual localization analysis. Three separated logistic models were calculated for interictal spikes, low-frequency magnetic activity, and the combination of both measures. A combined interictal spike/low-frequency magnetic activity model predicted correctly the operated temporal lobe in all patients. Clear-cut criteria for the probability model are proposed that are valid for 92.3% of cases in the sample. The quantitative approach proposed by this study is an evidence-based model for presurgical evaluation of temporal lobe epilepsy, which improves previous magnetoencephalographic investigations and establishes working clinical criteria for patient evaluation in TLE.journal articlehttps//doi.org/10.1097/00004691-200407000-00004http://journals.lww.com/clinicalneurophys/Abstract/2004/07000/Dipole_Density_of_Low_Frequency_and_Spike_Magnetic.4.aspxhttp://journals.lww.com/metadata only access51-76InterictalLow-frequency magnetic activityMagnetoencephalographyTemporal lobe epilepsyAdultEMTREE medical terms: adolescentComparative studyControlled studyDipoleEvidence based medicineAdultFemaleMaleHumanLogistic regression analysisMagnetismMagnetoencephalographyPreoperative evaluationSpikeStatistical modelTemporal lobe epilepsyVisual orientationElectroencephalographyEpilepsyTemporal LobeHumansLogistic ModelsMaleMiddle AgedModelsStatisticalPreoperative CareEstadística aplicadaBiología24 Ciencias de la Vida