Castrillo, GabrielSánchez-Bermejo, EduardoLorenzo, Laura deCrevillén, PedroFraile-Escanciano, AnaTC, MohanMouriz, AlfonsoCatarecha, PabloSobrino Plata, JuanOlsson, SannaLeo del Puerto, YolandaMateos, IsabelRojo, EnriqueHernández, LuisJarillo, JosePiñeiro, ManuelPaz-Ares, JavierLeyva, Antonio2024-02-062024-02-062013Gabriel Castrillo, Eduardo Sánchez-Bermejo, Laura de Lorenzo, Pedro Crevillén, Ana Fraile-Escanciano, Mohan TC, Alfonso Mouriz, Pablo Catarecha, Juan Sobrino-Plata, Sanna Olsson, Yolanda Leo del Puerto, Isabel Mateos, Enrique Rojo, Luis E. Hernández, Jose A. Jarillo, Manuel Piñeiro, Javier Paz-Ares, Antonio Leyva, WRKY6 Transcription Factor Restricts Arsenate Uptake and Transposon Activation in Arabidopsis , The Plant Cell, Volume 25, Issue 8, August 2013, Pages 2944–2957, https://doi.org/10.1105/tpc.113.1140091040-465110.1105/tpc.113.114009https://hdl.handle.net/20.500.14352/99288Stress constantly challenges plant adaptation to the environment. Of all stress types, arsenic was a major threat during the early evolution of plants. The most prevalent chemical form of arsenic is arsenate, whose similarity to phosphate renders it easily incorporated into cells via the phosphate transporters. Here, we found that arsenate stress provokes a notable transposon burst in plants, in coordination with arsenate/phosphate transporter repression, which immediately restricts arsenate uptake. This repression was accompanied by delocalization of the phosphate transporter from the plasma membrane. When arsenate was removed, the system rapidly restored transcriptional expression and membrane localization of the transporter. We identify WRKY6 as an arsenate-responsive transcription factor that mediates arsenate/phosphate transporter gene expression and restricts arsenate-induced transposon activation. Plants therefore have a dual WRKY-dependent signaling mechanism that modulates arsenate uptake and transposon expression, providing a coordinated strategy for arsenate tolerance and transposon gene silencing.engjournal article1532-298Xhttps://doi.org/10.1105/tpc.113.114009restricted accessFisiología vegetal (Biología)2417.19 Fisiología Vegetal