Ferrándiz, María JoséArdanuy, CarmenLinares, JosefinaBalsalobre, LuzGarcía Esteban, María TeresaG. de la Campa, Adela2025-10-272025-10-272011-12-20Ferrándiz, M.-J., Ardanuy, C., Liñares, J., Balsalobre, L., García, M. T., & De La Campa, A. G. (2011). New species genetic approach to identify strains of mitis group streptococci that are donors of rifampin resistance to Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy, 55(1), 368-372. https://doi.org/10.1128/AAC.00856-100066-480410.1128/AAC.00856-10https://hdl.handle.net/20.500.14352/125414This work was supported by Plan Nacional de IDI of Ministerio de Ciencia e Innovación (grant no. BIO2008-02154) and Comunidad de Madrid (grant no. COMBACT-S-BIO-0260/2006).Eight rifampin-resistant streptococci of the mitis group were identified at the species level by using a concatenated 16S rRNA gene-sodA-rpoB-hlpA sequence. Characterization of their rpoB alleles showed single amino acid changes involved in rifampin resistance. Comparison of RpoB sequences from pneumococcal recombinant isolates, viridans isolates, and type strains revealed a species-specific amino acid signature, which allowed it to be ascertained that recombinant RpoBs were originated in genetic interchanges with Streptococcus mitis and Streptococcus oralis.engjournal article1098-6596https://doi.org/10.1128/aac.00856-10https://journals.asm.org/doi/10.1128/aac.00856-10restricted access579.61616.9615.01/.03Microbiología (Biología)Enfermedades infecciosasFarmacología (Medicina)2414 Microbiología3205.05 Enfermedades Infecciosas3209 Farmacología