Moreno, DavidGiorgi, GiorgioSalas, CristianTapia, Ricardo2023-06-192023-06-192013-11-261420-304910.3390/molecules181214797https://hdl.handle.net/20.500.14352/34392In this report a short and efficient synthesis of the dibenz[b,f]oxepin framework through intramolecular SNAr and McMurry reactions is described. The diaryl ethers required for the McMurry reaction have been obtained in good yields under microwave-assisted conditions of the reaction of salicylaldehydes with fluorobenzaldehydes without catalysts. Application of an intramolecular McMurry reaction to the synthesized diarylethers using TiCl4/Zn in THF gave the target dibenzo[b,f]oxepin system in 53%–55% yields.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttps://doi.org/10.3390/molecules181214797https://www.mdpi.com/1420-3049/18/12/14797open access547dibenzoxepinsWittig reactionMcMurry reactionaromatic nucleophilic substitutionQuímica orgánica (Farmacia)