Martínez Alberquilla, IreneGarcía Montero, MaríaRuiz Alcocer, JavierCrooke Álvarez, AlmudenaMadrid Costa, David2023-06-172023-06-172020-11-23Martínez Alberquilla, I., García Montero, M., Ruiz Alcocer, J. et al. «Visual Function, Ocular Surface Integrity and Symptomatology of a New Extended Depth-of-Focus and a Conventional Multifocal Contact Lens». Contact Lens and Anterior Eye, vol. 44, n.o 5, octubre de 2021, p. 101384. DOI.org (Crossref), https://doi.org/10.1016/j.clae.2020.11.004.1367-048410.1016/j.clae.2020.11.004https://hdl.handle.net/20.500.14352/7859Purpose: To evaluate visual function, ocular surface integrity and dry eye symptoms with an extended depth-of-focus (EDOF) design and a conventional multifocal (MF) contact lens (CL) after 15 days of wear. Methods: A crossover single mask randomised clinical trial was conducted including 30 presbyopes who used an EDOF and a conventional MF CL (Biofinity MF) for 15 days each. Defocus curves, depth-of-focus range, contrast sensitivity (CS) under photopic and mesopic conditions (with and without glare) and subjective perception of halos and glare were evaluated. The ocular surface was evaluated through non-invasive Keratograph tear breakup time (NIKBUT), averaged tear breakup time (NIKBUT-avg), tear meniscus height (TMH), bulbar and limbal redness, and conjunctival and corneal staining. Dry eye symptoms were assessed with the OSDI questionnaire. Results: No statistically significant differences were found for defocus curves or depth-of-focus between the two CLs (both p > 0.05). Subjective perception of halos and glare was not significantly different between CLs. Statistically significant differences were observed for CS under mesopic conditions for low spatial frequencies (p = 0.008). None of the CL produced significant changes in NIKBUT, NIKBUT-avg, TMH or redness. No change in conjunctival staining was observed in 76.7 % and 73.3 % of participants for EDOF and Biofinity MF, respectively. No change in corneal staining was observed in 86.7 % and 83.3 % of participants for EDOF and Biofinity MF, respectively. No changes were observed in the symptomatology measured with OSDI questionnaire (p > 0.05). Conclusions: Both CL for presbyopia offer good visual quality, preserve the ocular surface integrity and provide the patient with similar symptomatology levels after 15 days of lens wear.engAtribución-NoComercial-SinDerivadas 3.0 Españahttps://creativecommons.org/licenses/by-nc-nd/3.0/es/journal articlehttps://doi.org/10.1016/j.clae.2020.11.004open access617.7-089.243617.753.4Extended depth-of-focusMultifocal contact lensPresbyopiaLentes de contactoOptometría3311.11 Instrumentos ópticos2209.15 Optometría