Fernández García, AitorZhou, YingGarcía Alonso, MercedesAndrango, HenryPoyales, FranciscoGarzón Jiménez, Nuria2023-11-202023-11-202020Fernández-García A, Zhou Y, García-Alonso M, Andrango HD, Poyales F, Garzón N. Comparing Medium-Term Clinical Outcomes following XEN® 45 and XEN® 63 Device Implantation. J Ophthalmol. 2020 Mar 23;2020:4796548.2090-004X10.1155/2020/4796548https://hdl.handle.net/20.500.14352/88865Purpose: To evaluate medium-term clinical outcomes with XEN® 45 or XEN® 63 Gel Stent (Allergan, Dublin, Ireland) for treatment of primary open angle glaucoma (POAG). Materials and Methods. Retrospective, descriptive, and observational study involving 40 patients implanted with a XEN® 45 Gel Stent and 34 implanted with a XEN® 63 Gel Stent who had undergone POAG surgery and had been followed up and controlled between 12 and 36 months. Results: IOP dropped from 18.02 ± 5.23 mmHg preop to 13.81 ± 1.88, 14.80 ± 2.23, and 14.62 ± 1.90 at 1, 2, and 3 years after surgery (p < 0.001) consecutively with XEN® 45 and from 19.00 ± 6.11 mmHg preop to 15.47 ± 2.45, 14.66 ± 2.45, and 15.46 ± 2.48 at 1, 2, and 3 years after surgery (p < 0.001) with XEN® 63. The number of drugs used by patients to treat their glaucoma decreased after undergoing surgery in both groups. Within the XEN® 45 group, mean changes at 1 year, 2 years, and 3 years amounted to 70%, 74.3%, and 37.5%, respectively, whereas within the XEN® 63 group, the mean reduction was 75%, 79.8%, and 71.9%. When comparing the outcomes for the two groups, the differences did not prove to be statistically significant. More than 90% of the procedures included in the study (using either gel-stent device) were completed without any noteworthy complications. Conclusion: POAG surgical procedures with either XEN® 45 or XEN® 63 Gel Stent implantation could be a safe and effective treatment approach.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal article2090-0058https://doi.org/10.1155/2020/4796548open access617.7-007.681617.7-089Glaucoma; primary open angle glaucoma; POAGOftalmologíaCirugía3201.09 Oftalmología3213.09 Cirugía Ocular