Sastre Ibáñez, MarinaMartínez De La Casa Fernández-Borrella, José MaríaRebolleda Fernández, GemaCifuentes Canorea, PilarMoreno, María NievesMorales Fernández, LauraSáenz Francés, FedericoGarcía Feijoo, Julián2023-06-172023-06-172018-01-01Sastre Ibáñez, M., Martínez De La Casa Fernández-Borrella, J. M., Rebolleda Fernández, G. et al. «Utility of Bruch Membrane Opening-Based Optic Nerve Head Parameters in Myopic Subjects». European Journal of Ophthalmology, vol. 28, n.o 1, enero de 2018, pp. 42-46. DOI.org (Crossref), https://doi.org/10.5301/ejo.5001022.1120-672110.5301/ejo.5001022https://hdl.handle.net/20.500.14352/12072Purpose: To evaluate whether the new rim analysis software with spectral-domain optical coherence tomography (SD-OCT) shows advantages over the retinal nerve fiber layer (RNFL) thickness in patients with moderate myopia. Methods: In this prospective cross-sectional study, we studied 65 healthy subjects, 37 with spherical refractive errors in the range of -3 to -6 D (moderate, G1) and 28 with less than -3 D (low/non-myopic, G0). All patients were examined with Heidelberg Spectralis SD-OCT, including Glaucoma Premium Module Edition (GPME) software. With GPME, we analyzed the neuroretinal rim (Bruch membrane opening-minimum rim width [BMO-MRW]) and RNFL. Results: The average age of subjects was 30.2 ± 9.3 years for G0 and 29.9 ± 7.1 years for G1 (p = 0.903). Mean sphere was −0.5 ± 0.3 D (-1.25 to 0 D) G0 and -3.9 ± 0.3 D (-6.00 to -3 D) G1 (p<0.001). The RNFL thickness comparison between G0 and G1 showed a significantly lower thickness in G1 (p = 0.018). The BMO-MRW measurements were similar in both groups (p = 0.331). With the BMO-MRW examination, the number of sectors classified as pathologic per subject in G1 were significantly lower compared to RNFL analysis (p = 0.023). Conclusions: Ring analysis based on BMO-MRW measurements shows a lower rate of false-positives compared to RNFL thickness when studying healthy moderate myopic eyes and it would be advisable to take this into consideration when analyzing these patients.engjournal articlehttps://doi.org/10.5301/ejo.5001022http://journals.sagepub.com/doi/abs/10.5301/ejo.5001022restricted access617.731-073.75617.753.2Bruch membrane openingMyopiaOptic nerve headOptical coherence tomographyRetinal nerve fiber layerDiagnóstico por imagen y medicina nuclearOftalmologíaOptometríaTécnicas de la imagen3204.01 Medicina Nuclear3201.09 Oftalmología2209.15 Optometría