Roscales García, SilviaSancho, AinhoaGarcía Csaky, Aurelio2025-01-212025-01-212015Synthesis 2015, 47, 2233–224110.1055/s-0034-1380525https://hdl.handle.net/20.500.14352/115322The regioselective conjugate addition of alkenylboronic acids to electronically-differentiated 1,4-enedicarbonyl compounds under metal-free conditions, using tartaric acid as promoter of the reaction is reported. The resulting compounds have been used as starting materials in the synthesis of 4-alkenyl-4,5-dihydropyridazin-3(2H)-ones or 4-alkylpyridazin-3(2H)-ones by reaction with hydrazine hydrate and acetic acid.engMetal-free conjugate addition of alkenylboronic acids to enedicarbonyl compounds towards the synthesis of pyridazine derivativesjournal articlehttps://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1380525restricted access547BoronCyclizationIsomerizationMichael additionNucleophilic additionQuímica orgánica (Química)2306 Química Orgánica