Carpena Torres, CarlosFerrando León, ElenaGarcía García, CarlaRomaguera, MaríaHuete Toral, FernandoCarracedo Rodríguez, Juan Gonzalo2024-05-242024-05-242024-04-01Carpena-Torres C, Ferrando E, García-García C, Romaguera M, Huete-Toral F, Carracedo G. In Vitro Evaluation of Soft Contact Lens Wettability With a Nonmodified Commercial Videokeratoscope. Eye Contact Lens. 2024 Apr 1;50(4):177-182. doi: 10.1097/ICL.0000000000001074. Epub 2024 Feb 1. PMID: 38305377.1542-232110.1097/ICL.0000000000001074https://hdl.handle.net/20.500.14352/104441Purpose: To evaluate a new in vitro technique for measuring soft contact lens wettability using a nonmodified commercial videokeratoscope, the Medmont E300. To this end, the capability of different artificial tears containing hyaluronic acid (HA) to improve soft contact lens wettability in vitro was investigated. Methods: An experimental in vitro study was conducted to assess the wetting properties of three artificial tears containing different concentrations of HA (0.1%, 0.2%, and 0.3%) on soft contact lenses. A saline solution was used as the control. For each solution, 15 hydrogel (Ocufilcon D) contact lenses and 15 silicone-hydrogel (Somofilcon A) contact lenses were evaluated. The in vitro wettability of the lenses was measured using the Medmont E300 with a self-developed technique, which involved measuring the tear film surface quality (TFSQ) mean, TFSQ area, TFSQ central, and TFSQ inferior. Results: Compared with the saline solution, all the concentration of HA (0.1%, 0.2%, and 0.3%) improved the in vitro wettability of both soft contact lenses by decreasing their TFSQ mean and TFSQ area (P<0.05). Regression models revealed an exponential relationship between contact lens wettability and the concentration of HA for both soft contact lenses (R>0.5, P<0.05). Furthermore, the hydrogel contact lens presented a wetter surface than the silicone-hydrogel contact lens (P<0.05). Conclusions: The measurement of in vitro wettability of soft contact lenses with a nonmodified Medmont E300 seems to be a useful technique to evaluate the wetting properties of contact lens products.engjournal article1542-233Xhttps://doi.org/10.1097/icl.000000000000107438305377https://journals.lww.com/claojournal/fulltext/2024/04000/in_vitro_evaluation_of_soft_contact_lens.4.aspxrestricted access617.7-089.243681.73617.764WettabilityHydrogelSilicone hydrogelHyaluronic acidArtificial tearsÓptica oftálmicaLentes de contactoOftalmologíaÓptica y optometría2209.15 Optometría3201.09 Oftalmología3311.09 Lentes