Luna Costales, AmparoEsteban Arderíus, PabloHerrera García, FernandoSan Martín Loubet, DanielAlmendros Requena, Pedro2025-01-172025-01-172022-08-10Esteban P, Herrera F, San Martín D, Luna A, Almendros P. Regioselectivity Switch Based on the Stoichiometry: Stereoselective Synthesis of Trisubstituted Vinyl Epoxides by Cu‐Catalyzed 3‐exo‐trig Cyclization of α‐Allenols. Advanced Synthesis & Catalysis. 2022, 364, 3289–3294.ISSN:1615-415010.1002/adsc.202200592https://hdl.handle.net/20.500.14352/114881Typical transition metal-catalyzed oxycyclization of allenols takes place at the terminal allene carbon via a 5-endo path and forms dihydrofurans. A copper-catalyzed protocol brought about a reversed regioselectivity, generating a series of trisubstituted epoxides through a 3-exo-cyclization/sulfonylation cascade. The current stoichiometry control of regioselectivity may open singular opportunities in chemical transformations.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal article1615-4169https://doi.org/10.1002/adsc.202200592https://onlinelibrary.wiley.com/doi/10.1002/adsc.202200592https://digital.csic.es/handle/10261/289436open access547AllenesCopperCyclizationRegioselectivitySulfonesQuímica orgánica (Química)2306 Química Orgánica2306.14 Química de Los Organosulfurados