Prados, AntonioCarpio Rodríguez, Ana MaríaBonilla, Luis L.2024-01-222024-01-222012Prados, A., Carpio Rodríguez, A. M. y Bonilla, L. L. «Spin-Oscillator Model for the Unzipping of Biomolecules by Mechanical Force». Physical Review E, vol. 86, n.o 2, agosto de 2012, p. 021919. https://doi.org/10.1103/PhysRevE.86.021919.1539-375510.1103/physreve.86.021919https://hdl.handle.net/20.500.14352/94350A spin-oscillator system models unzipping of biomolecules (such as DNA, RNA, or proteins) subject to an external force. The system comprises a macroscopic degree of freedom, represented by a one-dimensional oscillator, and internal degrees of freedom, represented by Glauber spins with nearest-neighbor interaction and a coupling constant proportional to the oscillator position. At a critical value Fc of an applied external force F, the oscillator rest position (order parameter) changes abruptly and the system undergoes a first-order phase transition. When the external force is cycled at different rates, the extension given by the oscillator position exhibits a hysteresis cycle at high loading rates, whereas it moves reversibly over the equilibrium force-extension curve at very low loading rates. Under constant force, the logarithm of the residence time at the stable and metastable oscillator rest position is proportional to F − Fc as in an Arrhenius law.engjournal article1550-2376https://doi.org/10.1103/physreve.86.021919https://journals.aps.org/pre/abstract/10.1103/PhysRevE.86.021919restricted accessFísica matemática2204 Física de Fluidos