Kossatz, SusanneGrandke, JuliaCouleaud, PierreLatorre, AlfonsoAires, AntonioCrosbie Staunton, KieranLudwig, RobertDähring, HeidiEttelt, VolkerLazaro Carrillo, AnaCalero Calero, MacarenaSader, MahaCourty, JoséVolkov, YuriPrina Mello, AdrieleVillanueva, AngelesSomoza, ÁlvaroCortajarena, AitziberMiranda, RodolfoHilger, Ingrid2024-01-102024-01-102015Kossatz, S., Grandke, J., Couleaud, P. et al. Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery. Breast Cancer Res 17, 66 (2015). https://doi.org/10.1186/s13058-015-0576-110.1186/s13058-015-0576-1https://hdl.handle.net/20.500.14352/92206Tumor cells can effectively be killed by heat, e.g. by using magnetic hyperthermia. The main challenge in the field, however, is the generation of therapeutic temperatures selectively in the whole tumor region. We aimed to improve magnetic hyperthermia of breast cancer by using innovative nanoparticles which display a high heating potential and are functionalized with a cell internalization and a chemotherapeutic agent to increase cell death.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal articlehttps://doi.org/10.1186/s13058-015-0576-1open access544Química física (Química)2307 Química Física