Limitations of spoligotyping and variable-number tandem-repeat typing for molecular tracing of Mycobacterium bovis in a high-diversity setting

Rodríguez Campos, SabrinaAranaz Martín, AliciaJuan Ferré, Lucía DeSáez Llorente, José LuisRomero Martínez, BeatrizBezos Garrido, JavierJiménez, AntonioMateos García, Ana IsabelDomínguez Rodríguez, Lucas José2023-06-202023-06-202011-091098-660X10.1128/JCM.00301-11https://hdl.handle.net/20.500.14352/45179This study describes the attempt to trace the first Mycobacterium bovis outbreak in alpacas (Lama pacos) in Spain by spoligotyping and variable-number tandem-repeat (VNTR) analysis. Due to high genotype diversity, no matching source was identified, but local expansion of a clonal group was found and its significance for molecular tracing is discussed.engLimitations of spoligotyping and variable-number tandem-repeat typing for molecular tracing of Mycobacterium bovis in a high-diversity settingjournal articlehttp://jcm.asm.org/content/49/9/3361.fullrestricted accessVeterinaria3109 Ciencias Veterinarias