Campuzano Ruiz, SusanaPedrero Muñoz, MaríaNikoleli, G.-P.Pingarrón Carrazón, José ManuelNikolelis, D.P.2023-06-172023-06-172017-03-150956-566310.1016/j.bios.2016.01.042https://hdl.handle.net/20.500.14352/18047Owing to the outstanding conductivity and biocompatibility as well as numerous other fascinating properties of two-dimensional (2D)-nanomaterials, 2D-based nanohybrids have shown unparalleled superiorities in the field of electrochemical biosensors. This review highlights latest advances in electrochemical immunosensors for clinical biomarkers based on different hybrid 2D-nanomaterials. Particular attention will be given to hybrid nanostructures involving graphene and other graphene-like 2Dlayered nanomaterials (GLNs). Several recent strategies for using such 2D-nanomaterial heterostructures in the development of modern immunosensors, both for tagging or modifying electrode transducers, are summarized and discussed. These hybrid nanocomposites, quite superior than their rival materials, will undoubtedly have an important impact within the near future and not only in clinical areas. Current challenges and future perspectives in this rapidly growing field are also outlined.engjournal articlehttps://ac.els-cdn.com/S0956566316300434/1-s2.0-S0956566316300434-main.pdf?_tid=e57454df-716f-48e4-a0ff-a49765abd4a0&acdnat=1520931523_c34a69c577893e754719b3b4e49c2a59open access543Hybrid 2D-nanomaterials Immunosensors Clinical biomarkersQuímica analítica (Química)2301 Química Analítica