Martinez Ovejero, CristinaEscudero García-Calderón, José AntonioThomas-Lopez, DanielHoefer, AndreasMoyano, GabrielMontero Serra, NataliaMartín Espada, María Del CarmenGonzález Zorn, Bruno2024-01-222024-01-222017Ovejero CM, Escudero JA, Thomas-Lopez D, Hoefer A, Moyano G, Montero N, Martin-Espada C, Gonzalez-Zorn B. 2017. Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals. Antimicrob Agents Chemother 61:10.1128/aac.02640-16. https://doi.org/10.1128/aac.02640-160066-480410.1128/aac.02640-16https://hdl.handle.net/20.500.14352/94363C.M.O. and J.A.E. designed the study, performed the experiments, analyzed and interpreted the results, and wrote the draft manuscript. C.M.-E. collected the samples, provided the isolates for this study, and revised and approved the final version of the manuscript. N.M. performed the experiments, D.T.L. and G.M. analyzed and interpreted the results, and A.H. revised the manuscript. B.G.Z. conceived, designed, and coordinated the study and revised and approved the final versión of the manuscript.In this study, we characterized two tigecycline-resistant Klebsiella pneumoniae isolates from dog urine samples. The isolates were genetically unrelated, belonging to sequence type 11 (ST11) and ST147, both classically related to human isolates. To the best of our knowledge, this is the first identification of tigecycline-resistant isolates from animals. We unveil here the worrisome circulation among animals of bacterial clones resistant to this last-resort antibiotic.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal article1098-6596https://doi.org/10.1128/aac.02640-16https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444156/open access636.09KlebsiellaDrugeffluxEffluxpumpsPetsPlasmidsTigecyclineVeterinaria3109 Ciencias Veterinarias