Sánchez Alonso, SergioCanal-Rivero, ManuelGarrido-Torres, NathaliaBaca-Garcia, EnriqueCrespo-Facorro, BenedictoBarrigón Estévez, María LuisaRuiz-Veguilla, Miguel2026-02-242026-02-242025Sanchez-Alonso, S., Canal-Rivero, M., Garrido-Torres, N., Baca-Garcia, E., Crespo-Facorro, B., Barrigon, M. L., & Ruiz-Veguilla, M. (2025). Obsessive-compulsive and catatonic symptoms in the early stages of psychosis: Are they related?. European archives of psychiatry and clinical neuroscience, 275(8), 2523–2533. https://doi.org/10.1007/s00406-025-02080-20940-13341433-849110.1007/s00406-025-02080-2https://hdl.handle.net/20.500.14352/1330362025 Acuerdos transformativos CRUEObjective: Catatonia and obsessive–compulsive symptoms (OCS) are frequently observed in patients with psychosis, even at early stages, yet their relationship remains unclear. This study aimed to examine the prevalence and association of catatonic symptoms and OCS in early-stage psychosis. Methods: Seventy patients aged 18–55 years with early-stage psychosis (illness duration < 5 years) were assessed within 72 h of admission. Catatonic symptoms were evaluated using the Bush Francis Catatonia Rating Scale (BFCRS), OCS with the Obsessive–Compulsive Inventory-Revised (OCI-R), and psychotic symptoms with the Positive and Negative Syndrome Scale (PANSS). Correlations between catatonic, obsessive–compulsive, and psychotic symptom dimensions were analyzed. Logistic regression assessed associations between symptom dimensions and catatonia. Results: Catatonic symptoms (BFCRS ≥ 3) were present in 64.3% of patients, and 40% scored above the OCI-R cut-off for clinically significant OCS. Patients with catatonia had significantly higher total OCI-R scores and higher scores across all OCI-R subscales. Strong correlations were observed between mental neutralization and washing OCI-R subscales and BFCRS scores. Logistic regression showed that higher disorganized (OR = 1.699, 95% CI: 1.141–2.529, p = 0.009) and obsessive–compulsive symptoms (OR = 1.253, 95% CI: 1.058–1.483, p = 0.009) were independently associated with increased odds of catatonia, while positive symptoms showed a significant negative association (OR = 0.796, 95% CI: 0.644–0.983, p = 0.034). Conclusions: There is a high prevalence of both catatonic and obsessive–compulsive symptoms in early-stage psychosis. Disorganized and obsessive–compulsive symptoms are independent risk factors for catatonia, while positive symptoms may be protective. These findings highlight the importance of comprehensive symptom assessment in this population.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/journal articlehttps://doi.org/10.1007/s00406-025-02080-241051428https://link.springer.com/journal/406open access616.89Catatonia; Early-stage psychosis; First-episode psychosis; Obsessive–compulsive symptoms; Psychosis.Medicina32 Ciencias Médicas