Cabanas, Ana MFuentes-Guajardo, MacarenaSáez, NicolásCatalán, DavidsonCollao-Caiconte, Patricio O.Martín Escudero, María Del Pilar2024-07-112024-07-112024Biosensors 2024, 14(1), 52; https://doi.org/10.3390/bios140100522079-637410.3390/bios14010052https://hdl.handle.net/20.500.14352/105957This study examines the relationship between physiological complexity, as measured by Approximate Entropy (ApEn) and Sample Entropy (SampEn), and fitness levels in female athletes. Our focus is on their association with maximal oxygen consumption (𝑉𝑂2,𝑚𝑎𝑥). Our findings reveal a complex relationship between entropy metrics and fitness levels, indicating that higher fitness typically, though not invariably, correlates with greater entropy in physiological time series data; however, this is not consistent for all individuals. For Heart Rate (HR), entropy measures suggest stable patterns across fitness categories, while pulse oximetry (𝑆𝑝𝑂2) data shows greater variability. For instance, the medium fitness group displayed an ApEn(HR) = 0.57±0.13 with a coefficient of variation (CV) of 22.17 and ApEn(𝑆𝑝𝑂2) = 0.96±0.49 with a CV of 46.08%, compared to the excellent fitness group with ApEn(HR) = 0.60±0.09 with a CV of 15.19% and ApEn(𝑆𝑝𝑂2) =0.85±0.42 with a CV of 49.46%, suggesting broader physiological responses among more fit individuals. The larger standard deviations and CVs for 𝑆𝑝𝑂2 entropy may indicate the body’s proficient oxygen utilization at higher levels of physical demand. Our findings advocate for combining entropy metrics with wearable sensor technology for improved biomedical analysis and personalized healthcare.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Exploring the hidden complexity: entropy analysis in pulse oximetry of female athletesjournal articleopen accessPulse oximeterApproximate entropySample entropyVO2,maxWomen’s response to exerciseMedicina32 Ciencias Médicas