Iglesias Velázquez, ÓscarXin Gao, BaoluoGonzález Fernández-Tresguerres, FranciscoSaez Alcaide, Luis MiguelLeco Berrocal, María IsabelTorres García Denche, Jesús2026-01-292026-01-292026-01-05Iglesias-Velázquez Ó, Xing Gao B, Tresguerres FGF, Sáez Alcaide LM, Leco Berrocal I, Torres García-Denche J. Digital Surgical Guides in Bone Regeneration: Literature Review and Clinical Case Report. Applied Sciences. 2026; 16(1):537. https://doi.org/10.3390/app160105372076-3417https://doi.org/10.3390/app16010537https://hdl.handle.net/20.500.14352/131289The present study describes a digitally guided workflow for the Split Bone Block Technique (SBBT) using standardized cortical and particulate allogeneic grafts in combination with custom-designed, 3D-printed surgical guides. The aim was to illustrate the feasibility of a donor-site-free alternative to the conventional autologous approach, which remains technically demanding and associated with increased morbidity. A narrative literature review and a single clinical case report were conducted to contextualize the proposed workflow. Digital planning was performed by merging DICOM and STL datasets to design cutting boxes for standardized allogeneic laminae and a transporter guide for intraoperative positioning. The technique was applied in a patient with severe horizontal ridge atrophy. Primary wound closure and uneventful healing were achieved. Six-month CBCT evaluation demonstrated an increase in horizontal ridge width from 2 mm to 8 mm. Within the limitations of a single illustrative case, this report suggests that a fully guided allogeneic SBBT workflow is feasible and may facilitate controlled graft adaptation while avoiding autologous bone harvesting. Further controlled clinical studies are required to evaluate accuracy, reproducibility, and long-term outcomes.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/journal articlehttps://doi.org/10.3390/app16010537https://www.mdpi.com/2076-3417/16/1/537open access[616.314-089:616.716.1]:004.896Split bone block techniqueAllogeneic graftCAD-CAMDigital workflow3D printingGuided bone regenerationOdontología (Odontología)Cirugía bucofacialImplantes dentalesDiseño por ordenador3201 Ciencias Clínicas3213.13 Ortodoncia-Estomatología3213 Cirugía2209.90 Tratamiento Digital. Imágenes