Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study

Castro Barquero, SaraTresserra Rimbau, AnnaVitelli Storelli, FacundoDoménech, MónicaSalas Salvadó, JordiMartín Sánchez, VicenteRubín García, MaríaBuil Cosiales, PilarCorella, DoloresFitó, MontserratRomaguera, DoraVioque, JesúsAlonso Gómez, Ángel MaríaWärnberg, JuliaMartínez, José AlfredoSerra Majem, LluísTinahones, Francisco JoséLapetra, JoséPintó, XavierTur, Josep AntonioGarcía Rios, AntonioGarcía Molina, LauraDelgado Rodríguez, MiguelMatía Martín, María Del PilarDaimiel, LidiaVidal, JosepVázquez, ClotildeCofán, MontserratRomanos Nanclares, AndreaBecerra Tomas, NereaBarragan, RocioCastañer, OlgaKonieczna, JadwigaGonzález Palacios, SandraSorto Sánchez, CarolinaPérez López, JessicaZulet, María ÁngelesBautista Castaño, InmaculadaCasas, RosaGómez Pérez, Ana MaríaSantos Lozano, José ManuelRodríguez Sánchez, María ÁngelesJulibert, AliciaMartín Calvo, NereaHernández Alonso, PabloSorlí, José VSanllorente, AlbertGalmés Panadés, Aina MaríaCases Pérez, EugenioGoicolea Güemez, LeireRuiz Canela, MiguelBabio, NancyHernáez, ÁlvaroLamuela Raventós, Rosa MaríaEstruch, Ramon2023-06-172023-06-172020-03-04Castro-Barquero, S.; Tresserra-Rimbau, A.; Vitelli-Storelli, F.; Doménech, M.; Salas-Salvadó, J.; Martín-Sánchez, V.; Rubín-García, M.; Buil-Cosiales, P.; Corella, D.; Fitó, M.; et al. Dietary Polyphenol Intake Is Associated with HDL-Cholesterol and A Better Profile of Other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study. Nutrients 2020, 12, 689, doi:10.3390/nu12030689.2072-664310.3390/nu12030689https://hdl.handle.net/20.500.14352/8255Dietary polyphenol intake is associated with improvement of metabolic disturbances. The aims of the present study are to describe dietary polyphenol intake in a population with metabolic syndrome (MetS) and to examine the association between polyphenol intake and the components of MetS. This cross-sectional analysis involved 6633 men and women included in the PREDIMED (PREvención con DIeta MEDiterranea-Plus) study. The polyphenol content of foods was estimated from the Phenol-Explorer 3.6 database. The mean of total polyphenol intake was 846 ± 318 mg/day. Except for stilbenes, women had higher polyphenol intake than men. Total polyphenol intake was higher in older participants (>70 years of age) compared to their younger counterparts. Participants with body mass index (BMI) >35 kg/m2 reported lower total polyphenol, flavonoid, and stilbene intake than those with lower BMI. Total polyphenol intake was not associated with a better profile concerning MetS components, except for high-density lipoprotein cholesterol (HDL-c), although stilbenes, lignans, and other polyphenols showed an inverse association with blood pressure, fasting plasma glucose, and triglycerides. A direct association with HDL-c was found for all subclasses except lignans and phenolic acids. To conclude, in participants with MetS, higher intake of several polyphenol subclasses was associated with a better profile of MetS components, especially HDL-c.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Studyjournal articlehttps://doi.org/10.3390/nu12030689https://www.mdpi.com/2072-6643/12/3/689open accessPolyphenolsMetabolic syndromeMediterranean dietGlignansStilbenesHDL-cholesterolDietética y nutrición (Medicina)3206 Ciencias de la Nutrición