García Martín, Elena SalobrarHoz Montañana, María Rosa DeRojas López, María BlancaRamírez Sebastián, Ana IsabelSalazar Corral, Juan JoséYubero Pancorbo, RaquelGil Gregorio, PedroTriviño Casado, AlbertoRamírez Sebastián, José Manuel2023-06-182023-06-182015-05-20García Martín, E. S., Hoz Montañana, M. R., Rojas López, M. B. et al. «Ophthalmologic Psychophysical Tests Support OCT Findings in Mild Alzheimer’s Disease». Journal of Ophthalmology, vol. 2015, 2015, pp. 1-10. DOI.org (Crossref), https://doi.org/10.1155/2015/736949.2090-004X10.1155/2015/736949https://hdl.handle.net/20.500.14352/24070Copyright © 2015 Elena Salobrar-Garcia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Purpose. To analyze in mild Alzheimer's disease (MAD) patients, GDS-4 (Reisberg Scale), whether or not some psychophysical tests (PTs) support OCT macular findings in the same group of MAD patients reported previously. Methods. Twenty-three MAD patients and 28 age-matched control subjects with mean Mini Mental State Examination of 23.3 and 28.2, respectively, with no ocular disease or systemic disorders affecting vision were included. Best-corrected visual acuity (VA), contrast sensitivity (CS) (3, 6, 12, and 18 cpds), color perception (CP), and perception digital test (PDT) were tested in one eye of each patient. Results. In comparison with the controls, MAD patients presented (i) a significant decrease in VA, PDT, and CS for all spatial frequencies analyzed, especially the higher ones, and (ii) a significant increase in unspecific errors on the blue axis (P < 0.05 in all instances). In MAD patients, a wide a ROC curve was plotted in all PTs. Conclusions. In MAD, CS, VA, and the tritan axis in CP were impaired. The PTs with the greatest predictive value are the higher spatial frequencies in CS and tritan unspecific errors in CP. PT abnormalities are consistent with the structural findings reported in the same MAD patients using OCT.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttp://dx.doi.org/10.1155/2015/736949http://www.hindawi.com/journals/joph/contents/open access617.735-073.75616.894-053.9OCTOptical Coherence TomographyNerve-Fiber LayerContrast SensivityCOognitive ImpairmentVisual DysfunctionRetinal PathologySenile DementiaAlzheimerDiagnóstico por imagen y medicina nuclearGeriatríaNeurociencias (Medicina)OftalmologíaAnatomía ocularTécnicas de la imagen3204.01 Medicina Nuclear3201.07 Geriatría2490 Neurociencias3201.09 Oftalmología