Carrasco Perera, José LuisDíaz Marsa, Marina FranciscaPastrana, Jose I.Molina, RosaBrotons, LoretoLópez-Ibor Alcocer, María InésLópez-Ibor Aliño, Juan José2025-01-292025-01-292018-01-02Carrasco JL, Díaz-Marsá M, Pastrana JI, et al. Hypothalamic-pituitary-adrenal axis response in borderline personality disorder without post-traumatic features. British Journal of Psychiatry. 2007;190(4):357-358. doi:10.1192/bjp.bp.106.0225900007-12501472-146510.1192/bjp.bp.106.022590https://hdl.handle.net/20.500.14352/116874Hypothalamic–pituitary–adrenal (HPA) axis sensitivity was investigated in 32 non-medicated patients with borderline personality disorder without comorbid post-traumatic syndromes and in 18 normal individuals using a modified dexamethasone suppression test (0.25 mg). Enhanced cortisol suppression was found in the patients v. controls (P < 0.05) and the percentage of participant's with non-suppression was smaller in the patient (34%) than in the control group (89%) (P < 0.01). Baseline cortisol levels in the patients were also lower than in the controls (P < 0.05). The 0.25 mg dexamethasone suppression test reveals increased feedback inhibition of the HPA in borderline personality disorder.engjournal articlehttps://doi.org/10.1192/bjp.bp.106.022590https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/hypothalamicpituitaryadrenal-axis-response-in-borderline-personality-disorder-without-posttraumatic-features/83A14A3E0B63BCE5CC6ED01E1645BBD3restricted access340.6Ciencias Biomédicas32 Ciencias Médicas