Molero Senosiain, MercedesMorales Fernández, LauraSáenz Francés, FedericoPerucho González, LucíaGarcía Bella, JavierGarcía Feijoo, JuliánMartínez De La Casa Fernández-Borrella, José María2023-06-172023-06-172020-12-10Molero Senosiain, M., Morales Fernández, L., Sáenz Francés, F. et al. «Corneal Properties in Primary Open-Angle Glaucoma Assessed Through Scheimpflug Corneal Topography and Densitometry». Journal of Glaucoma, vol. 30, n.o 5, mayo de 2021, pp. 444-50. DOI.org (Crossref), https://doi.org/10.1097/IJG.0000000000001770.1057-0829, 1536-481X10.1097/IJG.0000000000001770https://hdl.handle.net/20.500.14352/7753Purpose: To compare corneal topography and densitometry measurements in patients with primary open angle glaucoma (POAG) and healthy subjects. Patients and Methods: 200 eyes of 75 patients with POAG and 125 healthy controls underwent corneal topography and densitometry (Oculus Pentacam HR). The data compared in the two groups were: anterior chamber angle (ACA), depth (ACD) and volume (ACV), keratometry (K minimum, K maximum and K mean), central corneal thickness (CCT), central anterior elevation (CAE), anterior elevation apex (AEA), maximum anterior elevation (MAE) and posterior elevation apex (PEA). Densitometry measurements were made at three depths on a 12▒mm-diameter circle divided into 4 concentric rings (0-2▒mm, 2-6▒mm, 6-10▒mm and 10-12▒mm). The diagnostic capacity of the corneal variables was assessed through the areas under the receiver operator characteristics (ROC) curve (AUC). Results: The corneal density of practically all depth layers and total corneal density were significantly higher in the POAG than control group (P<0.05). Total corneal density was positively correlated with age (r=0.623; P<0.001) and also showed a good diagnostic capacity for glaucoma (AUC=0.617; IC 95% [0.541-0.697]; P<0.001). In a multiple linear regression designed to assess its relationship with age, gender, CCT and Km, age emerged as a significant confounder both in controls (coef. 0.315; P<0.001; 95% CI [0.246-0.384]) and patients (coef. 0.370; P<0.001; 95% CI [0.255-0.486]). Conclusion: Corneal densitometry measurements showed a good diagnostic capacity for POAG suggesting this type of examination could have clinical applications in the diagnosis and management of glaucoma.engAtribución-NoComercial-SinDerivadas 3.0 Españahttps://creativecommons.org/licenses/by-nc-nd/3.0/es/journal articlehttps://doi.org/10.1097/ijg.0000000000001770https://journals.lww.com/glaucomajournal/Abstract/9000/Corneal_Properties_in_Primary_Open_Angle_Glaucoma.97675.aspxopen access617.713-073.75617.7-007.681617.713-073.85611.84Corneal densitometryPRimary open angle glaucomaCorneal topographyScheimpflugOftalmologíaAnatomía ocularTécnicas de la imagen3201.09 Oftalmología