Sánchez Luna, Manuel RamónGonzález Pacheco, NoeliaSantos González, MartínTendillo Cortijo, Francisco Javier2024-02-062024-02-062021-12Sánchez-Luna M, González-Pacheco N, Santos-González M, Tendillo-Cortijo F. High-frequency Ventilation. Clin Perinatol. 2021 Dec;48(4):855-868. doi: 10.1016/j.clp.2021.08.003. Epub 2021 Oct 2. PMID: 34774213.0095-510810.1016/j.clp.2021.08.003https://hdl.handle.net/20.500.14352/99320High-frequency ventilation (HFV) is an alternative to conventional mechanical ventilation, with theoretic benefits of less risk of ventilator lung injury and more effectivity in washout CO2. Previous clinical studies have not demonstrated advantages of HFV in preterm infants compared with conventional ventilation, so rescue HFV has been used when severe respiratory insufficiency needs aggressive ventilator settings in immature infants. Today it is possible to measure, set directly, and fix tidal volume, which can protect the immature lung from large volumes and fluctuations of the tidal volume. This strategy can be used in preterm infants with respiratory failure needing invasive ventilation.engjournal articlehttps://www.sciencedirect.com/science/article/abs/pii/S0095510821000804?via%3Dihubhttps://pubmed.ncbi.nlm.nih.gov/34774213/restricted access615.816CO(2) eliminationHigh-frequency ventilationTidal volumeVentilation efficacyVolume guaranteeCiencias Biomédicas32 Ciencias Médicas