Salazar Roa, MaríaLorente Pérez, María Del MarOrea Soufi, AlbaDavila, DavidErazo, TatianaLizcano, JoseCarracedo, ArkaitzKiss-Toth, EndreVelasco Díez, Guillermo2025-11-042025-11-042015-10Salazar M, Lorente M, Orea-Soufi A, Dávila D, Erazo T, Lizcano J, Carracedo A, Kiss-Toth E, Velasco G. Oncosuppressive functions of tribbles pseudokinase 3. Biochemical Society Transactions 2015;43:1122–6. https://doi.org/10.1042/BST20150124.0300-512710.1042/BST20150124https://hdl.handle.net/20.500.14352/125713Tribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression.engjournal article1470-8752https://doi.org/10.1042/BST20150124https://www.sciencedirect.com/org/science/article/abs/pii/S1470875215001191restricted access577.2615.015616-006Animal models of cancerAutophagyCannabinoidsEndoplasmic reticulum (ER) stressTribbles pseudokinasesBiología molecular (Biología)Bioquímica (Biología)OncologíaFarmacología (Medicina)2403 Bioquímica2407 Biología Celular3201.01 Oncología3209 Farmacología