Gómez-Carpintero Jiménez, JorgeSánchez Cebrián, Juan DomingoGonzález Matilla, Juan FranciscoMenéndez Ramos, José Carlos2023-06-162023-06-162021-10-01Gómez-Carpintero Jiménez, J., Sánchez Cebrián, J. D., González Matilla, J. F. & Menéndez Ramos, J. C. «Mechanochemical Synthesis of Primary Amides». The Journal of Organic Chemistry, vol. 86, n.o 20, octubre de 2021, pp. 14232-37. DOI.org (Crossref), https://doi.org/10.1021/acs.joc.1c02350.0022-326310.1021/acs.joc.1c02350https://hdl.handle.net/20.500.14352/4599CRUE-CSIC (Acuerdos Transformativos 2021)Ball milling of aromatic, heteroaromatic, vinylic, and aliphatic esters with ethanol and calcium nitride afforded the corresponding primary amides in a transformation that was compatible with a variety of functional groups and maintained the integrity of a stereocenter α to carbonyl. This methodology was applied to α-amino esters and N-BOC dipeptide esters and also to the synthesis of rufinamide, an antiepileptic drug.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttps://doi.org/10.1021/acs.joc.1c02350https://pubs.acs.org/doi/abs/10.1021/acs.joc.1c02350open accessQuímica orgánica (Química)2306 Química Orgánica