Manzano García, Miguel2023-06-162023-06-162021-12-171999-492310.3390/pharmaceutics13122179https://hdl.handle.net/20.500.14352/4997RESEARCH ID K-3719-2014  (Miguel Manzano García) ORCID 0000-0001-6238-6111 (Miguel Manzano García)Twenty years ago, a group of bold scientists led by Prof Vallet-Regí suggested for the first time the use of mesoporous materials as potential drug delivery systems. Without knowing it, these pioneers unleashed the beast of creativity around the World because that original idea has been the inspiration of hundreds of scientific groups Worldwide for the design of many versatile delivery systems based on mesoporous materials with a variety of potential applications. Because the dream is not the destination, it is the journey, the present review aims to summarise the chain of events that catapulted a small and young research team from the grassroots of academia to the elite of the Biomedical Engineering.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttps://www.mdpi.com/journal/pharmaceuticshttps://www.ucm.es/valletregigroupopen accessSilica-based mesoporous materialsmesoporous silica nanoparticlescontrolled releasestimuli-responsive drug delivery.Materiales3312 Tecnología de Materiales