Meduni, FrancescoDavies, Leon N.Madrid Costa, DavidFratini, AntonioWolffsohn, James S.2023-06-172023-06-172018-021367-048410.1016/j.clae.2017.09.003https://hdl.handle.net/20.500.14352/12054Received 13 July 2017, Revised 28 August 2017, Accepted 8 September 2017, Available online 3 October 2017.Purpose: To characterise the anatomical parameters of the porcine eye for potentially using it as a laboratory model of dry eye. Methods: Anterior chamber depth and angle, corneal curvature, shortest and longest diameter, endothelial cell density, and pachymetry were measured in sixty freshly enucleated porcine eyeballs. Results: Corneal steepest meridian was 7.85 ± 0.32 mm, corneal flattest meridian was 8.28 ± 0.32 mm, shortest corneal diameter was 12.69 ± 0.58 mm, longest corneal diameter was 14.88 ± 0.66 mm and central corneal ultrasonic pachymetry was 1009 ± 1 μm. Anterior chamber angle was 28.83 ± 4.16°, anterior chamber depth was 1.77 ± 0.27 mm, and central corneal thickness measured using OCT was 1248 ± 144 μm. Corneal endothelial cell density was 3250 ± 172 cells/mm2. Conclusions: Combining different clinical techniques produced a pool of reproducible data on the porcine eye anatomy, which can be used by researchers to assess the viability of using the porcine eye as an in-vitro/ex-vivo model for dry eye. Due to the similar morphology with the human eye, porcine eyeballs may represent a useful and cost effective model to individually study important key factors in the development of dry eye, such as environmental and mechanical stresses.engjournal articlehttps://doi.org/10.1016/j.clae.2017.09.003https://www.elsevier.comrestricted access617.75612.84Porcine eyeIn vitroEx vivoDry eyeConfocal microscopyOptical coherence tomographyOftalmologíaOptometríaÓptica fisiológica3201.09 Oftalmología2209.15 Optometría