Alonso Gómez, José MiguelMuñoz, Maria Paz2024-01-112024-01-112018Alonso, J. M.; Muñoz, M. P. Heterobimetallic Catalysis: Platinum-Gold-Catalyzed Tandem Cyclization/C−X Coupling Reaction of (Hetero)Arylallenes with Nucleophiles. Angew. Chem. Int. Ed. 2018, 57, 4742-4746 DOI:10.1002/anie.201800670.1433-785110.1002/anie.201800670https://hdl.handle.net/20.500.14352/92595Heterobimetallic catalysis offers new opportunities for reactivity and selectivity but still presents challenges, and only a few metal combinations have been explored so far. Reported here is a Pt‐Au heterobimetallic catalyst system for the synthesis of a family of multi‐heteroaromatic structures through tandem cyclization/C−X coupling reaction. Au‐catalyzed 6‐cyclization takes place as the first fast step. Pt‐Au clusters are proposed to be responsible for the increased reactivity in the second step, that is, the intermolecular nucleophilic addition which occurs through an outer‐sphere mechanism by hybrid homogeneous‐heterogeneous catalysis.engjournal article1521-3773https://doi.org/10.1002/anie.201800670restricted access547Ciencias23 Química