González Soltero, RocíoBressa, CarloTabone, MariangelaClemente, SaraLarrosa Pérez, María Del MarBailén, María2024-05-292024-05-292023-10-31González Soltero R, Bressa C, Tabone M, Clemente S, Larrosa M, Bailén M. Associations between Vitamin D Receptor (VDR) Polymorphisms and Gut Microbiota in a Spanish Population Sample. Biology and Life Sciences Forum. 2023; 29(1):410.3390/iecn2023-15530https://hdl.handle.net/20.500.14352/1045562023 Descuento MDPIThis study examined the association between genetic variations in the Vitamin D Receptor (VDR) gene and the composition of gut microbiota in a Spanish population. The VDR gene plays a role in mediating the effects of vitamin D on gut microbiota composition. We analyzed 87 healthy participants from the Spanish Caucasian population and found that the genetic variations were in Hardy–Weinberg equilibrium. Through metataxonomic sequencing, we identified that the GG genotype from the VDR polymorphism rs731236 seems to be associated with the opportunistic genus Solobacterium, indicating that genetic variations may influence the composition of gut microbiota.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/conference paperhttps://doi.org/10.3390/IECN2023-15530https://www.mdpi.com/2673-9976/29/1/4open access575(075.8)579.61(075.8)Vitamin D Receptor (VDR) polymorphismsGut microbiotaSpanish populationrs2731236LefseGenética médicaMicrobiología médica2409 Genética2414 Microbiología