Almaraz Morocho, DavidBaumann, KlausMoreno Martín, FlorentinoSaiz Galdós, JesúsSánchez Iglesias, Iván2025-10-232025-10-232025-07-09Almaraz, D., Baumann, K., Moreno Martín, F., Sánchez-Iglesias, I., & Saiz, J. (2025). The relationship of religiosity, spirituality and health in Spanish cancer patients: Testing underlying psychological, social and behavioral pathways. BMC Psychology, 13, Article 760. https://doi.org/10.1186/s40359-025-03097-x2050-728310.1186/s40359-025-03097-xhttps://hdl.handle.net/20.500.14352/125297Background Religiosity and spirituality (R/S) are associated with health outcomes in cancer patients, yet the psychosocial and behavioral pathways involved remain insufficiently understood, particularly in Spain. This study examines specific R/S elements and pathways that may contribute to perceived physical health in this population. Methods A cross-sectional study was conducted with Spanish cancer patients (N = 351), recruited between October 2022 and April 2023. Participants were adults (18–80 years) with a non-terminal cancer diagnosis. The responses were obtained through a questionnaire that included sociodemographic and health variables, as well as validated scales measuring spirituality, religiosity, R/S struggles, psychological factors (gratitude, compassion, negative emotions), social support, health behaviors, and perceived physical health. Path analyses were performed with model fit evaluated using multiple indices (χ2, CFI, TLI, RMSEA, SRMR). Results The global model did not present a good fit to the data, as did the partial model of religiosity. In contrast, the partial models of spirituality and R/S struggles presented good fit indices and a high explained variance, showing that in both models negative emotions and gratitude act as significant mediating pathways between R/S and perceived physical health. Conclusions Despite the limitations caused by the low sample size and the apparent misspecification of the religiosity segment, findings from the partial models suggest that decreased negative emotions and increased gratitude promoted by higher levels of spirituality and lower levels of R/S struggles lead to better perceived physical health in cancer patients. These results highlight the need to integrate spirituality into patient care, often overlooked in Spanish healthcare. Recognizing these pathways could contribute to more holistic care approaches that incorporate R/S dimensions, potentially enhancing oncology patients’ quality of life.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/journal articlehttps://doi.org/10.1186/s40359-025-03097-xhttps://bmcpsychology.biomedcentral.com/articles/10.1186/s40359-025-03097-xopen access316.6.ReligionSpiritualityHealthCancerPatientsHolistic healthReligion and psychologyCiencias Sociales61 Psicología