Escudero García-Calderón, José AntonioMazel, Didier2023-06-182023-06-182017-091139-670910.2436/20.1501.01.295https://hdl.handle.net/20.500.14352/19290Vibrio cholerae is one of the deadliest pathogens in the history of humankind. It is the causative agent of cholera, a disease characterized by a profuse and watery diarrhoea that still today causes 95.000 deaths worldwide every year. V. cholerae is a free living marine organism that interacts with and infects a variety of organisms, from amoeba to humans, including insects and crustaceans. The complexity of the lifestyle and ecology of V. cholerae suggests a high genetic and phenotypic plasticity. In this review, we will focus on two peculiar genomic features that enhance genetic plasticity in this bacterium: the division of its genome in two different chromosomes and the presence of the superintegron, a gene capture device that acts as a large, low-cost memory of adaptive functions, allowing V. cholerae to adapt rapidly.engjournal articlehttp://revistes.iec.cat/index.php/IM/article/viewFile/144184/pdf_1354open accessvibrio choleraegenome plasticitysuperintegronMedicinaMicrobiología médicaVeterinariaMicrobiología (Veterinaria)Biología molecular (Biología)Ecología (Biología)Microbiología (Biología)32 Ciencias Médicas3201.03 Microbiología Clínica3109 Ciencias Veterinarias3109.05 Microbiología2415 Biología Molecular2401.06 Ecología animal2414 Microbiología