Legarda Ceballos, Ana L.del Olmo, EstherLópez-Abán, JulioEscarcena, RicardoBustos, Luis A.Fonseca Berzal, Cristina RosaGómez Barrio, AliciaDib, JuanSan Feliciano, ArturoMuro, Antonio2023-06-182023-06-182015-06-231420-304910.3390/molecules200611554https://hdl.handle.net/20.500.14352/23897Thirteen aminoalcohols and eight diamines were obtained and tested against Trypanosoma cruzi epimastigotes strains MG, JEM and CL-B5 clone. Some of them were equal or more potent (1.0–6.6 times) than the reference compound nifurtimox. From them, three aminoalcohols and two diamines were selected for amastigotes assays. Compound 5 was as potent as the reference drug nifurtimox against amastigotes of the CL-B5 strain (IC50 = 0.6 µM), with a selectivity index of 54.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttps://doi.org/10.3390/molecules200611554https://www.mdpi.com/1420-3049/20/6/11554open access576.8aminoalcoholsdiaminesTrypanosoma cruziepimastigotesamastigotescytotoxicityParasitología (Farmacia)