Rawat, AmitRegueiro González-Barros, José RamónBriones Contreras, AlejandroSingh, Surjit2024-07-122024-07-122021-04-28Rawat, A., Singh, A., Dobbs, K. et al. Skewed TCR Alpha, but not Beta, Gene Rearrangements and Lymphoma Associated with a Pathogenic TRAC Variant. J Clin Immunol 41, 1395–1399 (2021). https://doi.org/10.1007/s10875-021-01047-x10.1007/s10875-021-01047-xhttps://hdl.handle.net/20.500.14352/106044We report a non-consanguineous family from North-west India in which 3 siblings succumbed to a rare variant of combined immunodeficiency. All three had similar clinical and immunological profiles. However, the youngest child also developed Non-Hodgkin lymphoma in infancy. Genetic analysis revealed a previously reported variant in the T cell receptor alpha constant (TRAC) gene.engworking paper1573-2592https://doi.org/10.1007/s10875-021-01047-xrestricted access612.017Non-Hodgkin lymphomaRearrangementsSevere combined immunodeficiencyT cell receptor alpha constant geneInmunología2412 Inmunología