Ji, ZichenMiguel Díez, Javier DeCastro Riera, Christian ReynaldoBellón Cano, José MaríaGallo González, VirginiaGirón Matute, Walther IvánJiménez García, RodrigoLópez De Andrés, Ana IsabelMoya Álvarez, VirginiaPuente Maestu, LuisHernández Vázquez, Julio2023-06-172023-06-172020-03-05Ji, Z., Miguel Díez, J., Castro Riera, C. R. et al. «Differences in the Outcome of Patients with COPD According to Body Mass Index». Journal of Clinical Medicine, vol. 9, n.o 3, marzo de 2020, p. 710. DOI.org (Crossref), https://doi.org/10.3390/jcm9030710.2077-038310.3390/jcm9030710https://hdl.handle.net/20.500.14352/8202Background: In chronic obstructive pulmonary disease (COPD), the “obesity paradox” is a phenomenon without a clear cause. The objective is to analyze the complications of COPD patients according to their body mass index (BMI). Methods: An observational study with a six-year prospective follow-up of 273 COPD patients who attended a spirometry test in 2011. Survival and acute events were analyzed according to the BMI quartiles. Results: A total of 273 patients were included. BMI quartiles were ≤24.23; 24.24–27.69; 27.70–31.25; ≥31.26. During the follow-up, 93 patients died. No differences were found in exacerbations, pneumonia, emergency visits, hospital admissions or income in a critical unit. Survival was lower in the quartile 1 of BMI with respect to each of the 2–4 quartiles (p-value 0.019, 0.013, and 0.004, respectively). Advanced age (hazard ratio, HR 1.06; 95% confidence interval, CI 1.03–1.09), low pulmonary function (HR 0.93; 95% CI 0.86–0.99), exacerbator with chronic bronchitis phenotype (HR 1.76; 95% CI 1.01–3.06), high Charlson (HR 1.32, 95% CI 1.18–1.49), and the quartile 1 of BMI (HR 1.99, 95% CI 1.08–3.69) were identified as risk factors independently associated with mortality. Conclusions: In COPD, low BMI conditions a lower survival, although not for having more acute events.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttps://doi.org/10.3390/jcm9030710https://www.mdpi.com/2077-0383/9/3/710open accessChronic obstructive pulmonary disease (COPD)Body mass indexSurvivalRisk factorDietética y nutrición (Medicina)3206 Ciencias de la Nutrición