Tabero, AndreaGarcía-Garrido, FernandoPrieto Castañeda, AlejandroPalao, EduardoRodríguez Agarrabeitia, AntoniaGarcía-Moreno, InmaculadaVillanueva Valdés, Miguel ÁngelMoya Cerero, Santiago De LaOrtiz, María José2024-01-082024-01-082019-12-11Tabero, A.; García-Garrido, F.; Prieto-Castañeda, A.; Palao, E.; Agarrabeitia, A. R.; García-Moreno, I.; Villanueva, A.; De la Moya, S., Chem. Commun., 2020, 56, 940-94310.1039/c9cc09397dhttps://hdl.handle.net/20.500.14352/91823Endowing BODIPY PDT agents with the ability to probe lipid droplets is demonstrated to boost their phototoxicity, allowing the efficient use of highly fluorescent dyes (poor ROS sensitizers) as phototoxic agents. Conversely, this fact opens the way to the development of highly bright ROS photosensitizers for performing photodynamic theragnosis (fluorescence bioimaging and photodynamic therapy) from a single simple agent. On the other hand, the noticeable capability of some of the reported dyes to probe lipid droplets in different cell lines under different conditions reveals their use as privileged probes for advancing the study of interesting lipid droplets by fluorescence microscopy.engjournal articlehttps://doi.org/10.1039/c9cc09397drestricted access547BODIPYLipid DropletsTheragnosis PhotodynamicQuímica orgánica (Química)Biología celular (Biología)2306 Química Orgánica2407 Biología Celular