Escobedo-Ruíz, AraceliBarquera, RodrigoGonzález-Martín, AntonioArgüelles-San Millán, Juan ManuelUribe-Duarte, María GuadalupeIraíz Hernández-Zaragoza, DianaClayton, StephenArrieta-Bolaños, EstebanRuíz Corral, María de JesúsGoné-Vázquez, IsisArellano-Prado, Francia PaulinaMartínez-Álvarez, Julio CésarGarcía-Arias, Víctor EduardoRodríguez-López, Marla EstefaníaBravo-Acevedo, AliciaSánchez-Fernández, María Guadalupe de JesúsAguilar-Campos, Jesús AbrahamGómez-Navarro, BenjamínSandoval-Sandoval, Mario J.Serrano-Osuna, RicardoYunis, Edmond J.Zúñiga, JoaquínBekker-Méndez, CarolinaGranados, Julio2023-06-172023-06-172019-06-110198-8859, ESSN: 1879-116610.1016/j.humimm.2019.06.007https://hdl.handle.net/20.500.14352/13846We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 250 Mexicans from the states of Baja California Norte and Baja California Sur living in Mexicali (N = 100), La Paz (N = 75), Tijuana (N = 25) and rural communities (N = 50) to obtain information regarding allelic and haplotypic frequencies. The most frequent haplotypes for the Baja California region include nine Native American and five European haplotypes. Admixture estimates revealed that the main genetic components are European (50.45 ± 1.84% by ML; 42.03% of European haplotypes) and Native American (43.72 ± 2.36% by ML; 40.24% of Native American haplotypes), while the African genetic component was less apparent (5.83 ± 0.98% by ML; 9.36% of African haplotypes).engjournal articlehttps://www.sciencedirect.com/science/article/pii/S0198885919305816open access575.17(72)HLAImmunogeneticsPopulation geneticsBaja CaliforniaAdmixtureGenética2409 Genética