Bonanad, ClaraEsteve Claramunt, FranciscaGarcía Blas, SergioAyesta, AnaDíez Villanueva, PabloPérez Rivera, Jose-ÁngelFerreiro, José LuisCánoves, JoaquimLópez Fornás, FranciscoAriza Solé, AlbertRaposerias, SergioVivas, DavidBlanco, ReginaBompart Berroterán, DazniaCordero, AlbertoNúñez, JulioFácila, LorenzoNúñez Gil, Iván J.Górriz, José LuisBodí, VicenteMartínez-Sellés D Oliveira Soares, ManuelRuiz Nodar, Juan MiguelChorro, Francisco Javier2023-06-222023-06-222022-05-262077-038310.3390/jcm11113008https://hdl.handle.net/20.500.14352/71726The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttps://doi.org/10.3390/jcm11113008https://www.mdpi.com/2077-0383/11/11/3008/htmopen accessacute coronary syndromeelderlyantiplatelet therapyclopidogrelprasugrelticagrelorCardiología3205.01 Cardiología