Alba Lasso, GuzmánPereda, ErnestoMañas, SoledadMéndez, Leopoldo D.Duque, María RosarioGonzález, AlmudenaGonzález, Julián J.2026-01-152026-01-152016-02Alba, G., Pereda, E., Mañas, S., Méndez, L. D., Duque, M. R., González, A., & González, J. J. (2016). The variability of EEG functional connectivity of young ADHD subjects in different resting states. Clinical neurophysiology, 127(2), 1321-1330. https://doi.org/10.1016/j.clinph.2015.09.13410.1016/j.clinph.2015.09.134https://hdl.handle.net/20.500.14352/130344Objective: To assess ADHD from global measures of EEG functional connectivity and their temporal variability in different resting states. Methods: EEGs from sixteen cortical regions were recorded at rest during eyes-closed (EC) and eyes-open (EO) in 10 male combined-type ADHD subjects and 12 healthy male controls. The mean global connectivity (CM) of each region and its temporal variability (CV) were estimated from a number of EEG segments recorded in both states. Connectivity indices between regions were calculated using the magnitude squared coherence (Coh) in the delta(d)/theta(h)/alpha(a)/beta(b) frequency bands and the nonlinear index (L) of generalized synchronization. Results: The CM did not present between-group differences in any region or state. However, the CV exhibited state-independent differences between both groups (ADHD > controls) mainly in frontal and parieto-occipital regions for all indices except Coh(a). Within group, only the CV-Coh(h) of the centrotemporal region increased significantly for the ADHD subjects from EC to EO (p < 0.001) and was greater than controls in EO (p < 0.001). Conclusions: The CV of index-L and of Coh(h) seem to be the best state-independent and-dependent measurements, respectively, to discriminate ADHDs from control subjects using resting state EEG data. Significance: The underlying neural dysfunctions producing the ADHD seem better reflected by the CV measurements.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal articlehttps://doi.org/10.1016/j.clinph.2015.09.134open access612.8:159.9Functional connectivityEEGADHDCoherenceGeneralized synchronizationResting stateNeuropsicología6106.01 Actividad Cerebral