Streptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones

Alou Cervera, LuisRamirez, MarioGarcı́a-Rey, CésarPrieto Prieto, Joséde Lencastre, Hermı́nia2024-07-232024-07-232001-10Alou L, Ramirez M, García-Rey C, Prieto J, de Lencastre H. Streptococcus pneumoniae isolates with reduced susceptibility to ciprofloxacin in Spain: clonal diversity and appearance of ciprofloxacin-resistant epidemic clones. Antimicrob Agents Chemother. 2001 Oct;45(10):2955-7. doi: 10.1128/AAC.45.10.2955-2957.20010066-48041098-659610.1128/aac.45.10.2955-2957.2001https://hdl.handle.net/20.500.14352/107054ABSTRACT Analysis of the pulsed-field gel electrophoretic profiles of 82 pneumococcal isolates with reduced susceptibility to ciprofloxacin (RSC) and of 90 co-occurring susceptible isolates indicates a considerable genetic diversity among isolates with RCS and points to a close relation between the two groups. This finding suggests that pneumococci with RCS emerge through independent mutational events.engStreptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clonesjournal articlehttps://doi.org/10.1128/aac.45.10.2955-2957.2001https://journals.asm.org/doi/10.1128/aac.45.12.3678-3678.2001restricted access611.02Microbiología médica2414 Microbiología