Escribano Subías, María PilarMesquida, AinaLópez Montesinos, SaraReigadas, ElenaMuñoz, PatriciaGuinea, JesúsMuñoz García, Patricia CarmenReigadas Ramírez, Elena Manuela2025-04-042025-04-042023Pilar Escribano, Aina Mesquida, Sara López-Montesinos, Elena Reigadas, Patricia Muñoz, Jesús Guinea, Amphotericin B, itraconazole, posaconazole, and isavuconazole MICs against clinical Mucorales isolates obtained by visual inspection and spectrophotometric reading according to the EUCAST 9.4 procedure, Medical Mycology, Volume 61, Issue 5, May 2023, myad045, https://doi.org/10.1093/mmy/myad0451369-37861460-270910.1093/mmy/myad045https://hdl.handle.net/20.500.14352/119230Fondo de Investigación Sanitaria Plan Nacional de I+D+I 2017-2020 European Regional Development Fund (FEDER) ‘A way of making Europe’We compared the antifungal susceptibility of 92 Mucorales isolates obtained by visual inspection and spectrophotometric readings following EUCAST (European Committee on Antimicrobial Susceptibility Testing) testing. Amphotericin B minimum inhibitory concentrations (MICs) were up to 1 mg/l against most isolates and variable among species, except for Cunninghamella bertholletiae. Posaconazole MICs against most isolates were up to 1 mg/l and high against Mucor circinelloides, some Rhizopus arrhizus, and Rhizopus microsporus. Isavuconazole MICs ranged between 1 and 8 mg/l but were invariably >8 mg/l against M. circinelloides and C. bertholletiae. The agreement between MICs obtained by visual endpoint or spectrophotometric readings was moderate and higher when using the ≥90% fungal growth inhibition endpoint.engjournal articlehttps://doi.org/10.1093/mmy/myad045https://academic.oup.com/mmy/article-abstract/61/5/myad045/7146205?redirectedFrom=fulltextrestricted access61MucoralesEUCASTisavuconazolespectrophotometric readingsMICCiencias Biomédicas32 Ciencias Médicas