Enríquez Rodríguez, EduardoAmat Santos, Ignacio J.Jiménez Quevedo, PilarMartín Morquecho, IreneTirado Conte, GabrielaPérez-Vizcayno, María JoséGómez de Diego, José JuanArnold, RomanAldazábal, AndrésRojas, PaolAgustín, Alberto deTrigo, María DelGutiérrez, HipólitoSan Román, José A.Macaya Miguel, CarlosNombela Franco, Luis2026-03-022026-03-022017-11-28Enríquez-Rodríguez E, Amat-Santos IJ, Jiménez-Quevedo P, Martín-Morquecho I, Tirado-Conte G, Pérez-Vizcayno MJ, et al. Comparación de la hemodinámica valvular de la prótesis transcatéter con balón expandible SAPIEN 3 frente a la autoexpandible Evolut R: estudio de casos emparejados. Revista Española de Cardiología 2018;71:735–42. https://doi.org/10.1016/j.recesp.2017.10.03210.1016/j.rec.2017.10.025https://hdl.handle.net/20.500.14352/133626Introduction and objectives: The SAPIEN 3 (S3) valve and the Medtronic Evolut R (EVR) are secondgeneration transcatheter valves, designed to further reduce the rate of paravalvular aortic regurgitation (AoR). The aim of this study was to compare the 2 devices in terms of valve performance in a casematched study with independent echocardiographic analysis. Methods: Of a population of 201 patients who underwent transcatheter aortic valve implantation, 144 patients (S3, n = 80; EVR, n = 64) were matched according to aortic annulus diameter and aortic valve calcium score, as assessed by computed tomography. All echocardiographic examinations collected at baseline and at 1- and 6-month follow-up were centrally analyzed. Results: The 2 groups were well balanced in baseline clinical and echocardiographic characteristics. The EVR valve showed a better hemodynamic profile as assessed by peak aortic gradient (EVR 13 7 vs S3 20 10 mmHg; P < .001), mean aortic gradient (EVR 7 3 vs S3 11 6 mmHg; P < .001), and Doppler velocity index (EVR 0.65 0.15 vs S3 0.51 0.16; P < .001). The rate of moderate-severe or any paravalvular ( mild) AoR was higher in the EVR group (11% and 50%) than in the S3 group (2.5% and 21%; P < .05, respectively), with a larger number of paravalvular jets (P < .001). Conclusions: In a case-matched cohort of transcatheter aortic valve implantation patients, the S3 valve was associatedwitha lower rate ofparavalvularAoR but alsowithahigher residual gradientthanthe EVRsystem.engjournal articlehttps://doi.org/ 10.1016/j.rec.2017.10.025https://www.sciencedirect.com/science/article/abs/pii/S0300893217306310?via%3Dihubrestricted accessCardiología3205.01 Cardiología