Velasco Díez, GuillermoLorente Pérez, María Del MarTorres, SofiaSalazar Roa, MaríaCarracedo, ArkaitzHernández Tiedra, SoniaRodríguez Fornés, FátimaGarcía Taboada, ElenaMeléndez, BárbaraMollejo, ManuelaCampos Martín, YolandaBarcia Albacar, Juan AntonioGuzmán Pastor, ManuelVelasco Díez, Guillermo2024-01-312024-01-312011Lorente, M., Torres, S., Salazar, M., Carracedo, A., Hernández-Tiedra, S., Rodríguez-Fornés, F., … Velasco, G. (2011). Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death. Autophagy, 7(9), 1071–1073. https://doi.org/10.4161/auto.7.9.158661554-862710.4161/auto.7.9.15866https://hdl.handle.net/20.500.14352/97335Δ9-tetrahydrocannabinol (THC), the main active component of marijuana, promotes cancer cell death via autophagy stimulation. We find that activation of the tyrosine kinase receptor ALK by its ligand midkine interferes with the signaling mechanism by which THC promotes autophagy-mediated glioma cell death.engStimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell deathjournal article1554-8635https://doi.org/10.4161/auto.7.9.15866restricted accessAutophagyGliomaCannabinoidsMidkineALKER stressTRB3Biología celular (Biología)2403 Bioquímica