Pérez Núñez, ÁngelLagares Gómez-Abascal, AlfonsoBenítez, J.Urioste, M.Díez Lobato, RamiroRicoy Campo, José RamónRamos González, AnaGonzález, P.2025-01-232025-01-232004-05-21Pérez-Núñez A, Lagares A, Benítez J, Urioste M, Lobato RD, Ricoy JR, Ramos A, González P. Lhermitte-Duclos disease and Cowden disease: clinical and genetic study in five patients with Lhermitte-Duclos disease and literature review. Acta Neurochir (Wien). 2004 Jul;146(7):679-900001-626810.1007/s00701-004-0264-xhttps://hdl.handle.net/20.500.14352/115800Lhermitte-Duclos Disease (LDD) is an infrequent cerebellar disorder characterized by focal or diffuse enlargement of cerebellar folia presenting as a slowly growing mass in the posterior fossa. Over the past decade its association with Cowden disease (CD) has been recognized with increasing frequency. This latter disease is a genetic condition leading to the presence of multiple hamartomas and neoplasias which affect mainly the skin, thyroid, breast and genito-urinary and gastro-intestinal tracts. It has even been hypothesized that LDD and CD constitute a single entity. This work is aimed to analyse to what extent this association was present in patients treated for LDD at our institution.engjournal article0942-0940https://doi.org/10.1007/s00701-004-0264-xhttps://link.springer.com/article/10.1007/s00701-004-0264-x#citeasrestricted access616-073.7Lhermitte-Duclos diseaseCowden diseasePTEN genecerebellumgangliocytomadysplasiaDiagnóstico por imagen y medicina nuclear3201.11 Radiología